Determination of the Main Solid-State Form of Albendazole in Bulk Drug, Employing Raman Spectroscopy Coupled to Multivariate Analysis. Natalia L. Calvo, Aida Ben Altabef, Marcelo Arias, Rubén M. Maggio y Teodoro S. Kaufman. J. Pharm. Biomed. Anal. 129, 190-197 (2016). J Pharm Biomed Anal 2016 129 190.pdf
 
Mebendazole Crystal Forms in Tablet Formulations. An ATR-FTIR/Chemometrics Approach to Polymorph Assignment. Natalia L. Calvo, Rubén M. Maggio y Teodoro S. Kaufman. J. Pharm. Biomed. Anal. 122, 157-165 (2016).  J Pharm Biomed Anal 2016 122 157.pdf
 

Preparation and Physical Characterization of a Diclofenac-Ranitidine Co-precipitate for Improving the Dissolution of Diclofenac. Robertino O. Gaitano, Natalia L. Calvo, Griselda E. Narda, Teodoro S. Kaufman, Rubén M. Maggio y Elena V. Brusau. J. Pharm. Sci. 105, 1258-1268 (2016).J Pharm Sci 2016 105 1258.pdf

Thermally Induced Solid-State Transformation of Cimetidine. A Multi-spectroscopic/Chemometrics Determination of the Kinetics of the Process and Structural Elucidation of one of the Products as a Stable N3-Enamino Tautomer. Natalia L. Calvo, Sebastian O. Simonetti, Rubén M. Maggio, Teodoro S. Kaufman. Anal. Chim. Acta 875, 22-32 (2015). Anal Chim Acta 2015 875 22.pdf (1691724)

A PCA-Based Chemometrics-Assisted ATR-FTIR Approach for the Classification of Polymorphs of Cimetidine. Application to Physical Mixtures and Tablets. Natalia L. Calvo, Rubén M. Maggio y Teodoro S. Kaufman. J. Pharm. Biomed. Anal. 107, 419-425 (2015). J Pharm Biomed Anal 2015 107 419.pdf (1029664)

Pharmaceutical Impurities and Degradation Products: Uses and Applications of NMR Techniques. Rubén M. Maggio, Natalia L. Calvo, Silvana E. Vignaduzzo y Teodoro S. Kaufman. J. Pharm. Biomed. Anal. 101, 102-122 (2014). J Pharm Biomed Anal 2014 101 102.pdf (2664671)
 
A Dynamic Thermal ATR-FTIR/Chemometrics Approach to the Analysis of Polymorphic Interconversions. Cimetidine as a Model Drug”, Natalia L. Calvo, Rubén M. Maggio y Teodoro S. Kaufman. J. Pharm. Biomed. Anal. 92, 90-97 (2014). J Pharm Biomed Anal 2014 92 90.pdf (1129529)
 
An Eco-Friendly Strategy, using On-Line Monitoring and Dilution Coupled to a Second-Order Chemometric Method, for the Construction of Dissolution Curves of Combined Pharmaceutical Associations”. Natalia L. Calvo, Rubén M. Maggio y Teodoro S. Kaufman. J. Pharm. Biomed. Anal. 89, 213-220 (2014).  J Pharm Biomed Anal 2014 89 213.pdf (986591)
 
Stability-indicating Methods for the Assay of Bulk Drugs and Drug Formulations. A Regulatory Perspective. Rubén M. Maggio, Silvana E. Vignaduzzo y Teodoro S. Kaufman. Trends in Anal. Chem. 49, 57-70 (2013). Trends Anal Chem 2013 49 57.pdf (1352631)
 
A Multivariate Curve Resolution Approach to the Study of the Degradation Kinetics of Valsartan Under Photolytic and Acid Conditions. Romina M. Bianchini and Teodoro S. Kaufman. Int. J. Chem. Kinet. 45, 734-743 (2013).  Int J Chem Kinet 2013 45 734.pdf (863912)
 
Development and Validation of an HPLC Method for the Simultaneous Determination of Bromhexine, Chlorpheniramine, Paracetamol and Pseudoephedrine in their Combined Cold Medicine Formulations. Silvana E. Vignaduzzo y Teodoro S. Kaufman. J. Liq. Chromatogr. Relat. Technol. 36, 2829-2843 (2013). J Liq Chromatogr Relat Technol 2013 36 2829.pdf (516341)
 
Simultaneous Acquisition of the Dissolution Curves of Two Active Ingredients in a Binary Pharmaceutical Association, Employing an On-line Circulation System and Chemometrics-Assistance. Rubén M. Maggio, María A. Rivero y Teodoro S. Kaufman. J. Pharm. Biomed. Anal. 72, 51-58 (2013). J Pharm Biomed Anal 2013 72 51.pdf (706472)
 
Stress Testing of Valsartan. Development and Validation of a High Performance Liquid Chromatography Stability-Indicating Assay. Romina M. Bianchini, Patricia M. Castellano y Teodoro S. Kaufman. J. Liq. Chromatogr. Relat. Technol. 35, 1053-1069 (2012). J Liq Chromatogr Relat Technol 2012 35 1053.pdf (705722)
 
Multivariate Optimization and Validation of a CZE Method for the Analysis of Pridinol Mesylate and Meloxicam in Tablets. Silvana E. Vignaduzzo, Luciana Vera-Candioti, Patricia M. Castellano, Héctor C. Goicoechea y Teodoro S. Kaufman. Chromatographia 74, 609-617 (2011). Chromatographia 2011 609.pdf (1772625)
 
Development and Validation of an HPLC Method for the Simultaneous Determination of Amlodipine, Hydrochlorothiazide and Valsartan in Tablets of Their Novel Triple Combination and Binary Pharmaceutical Associations. Silvana E. Vignaduzzo, Patricia M. Castellano y Teodoro S. Kaufman. J. Liq. Chromatogr. Relat. Technol. 34, 2383-2395 (2011). J Liq Chromatogr Relat Technol 2011 34 2383.pdf (621426)
 
Characterization of Two New Potential Impurities of Valsartan Obtained Under Photodegradation Stress Condition. Romina M. Bianchini, Patricia M. Castellano y Teodoro S. Kaufman. J. Pharm. Biomed. Anal. 56,  16-22 (2011). J Pharm Biomed Anal 2011 56 16.pdf (684713)
 
Experimentally Designed, Validated HPLC Simultaneous Determination of Pridinol and Diclofenac in their Combined Pharmaceutical Formulations, which Allows Limiting Diclofenac Related Compound A. Silvana E. Vignaduzzo, Patricia M. Castellano y Teodoro S. Kaufman. J. Liq. Chromatogr. Relat. Technol. 33, 1720-1732 (2010). J Liq Chromatogr Relat Technol 2010 33 1720.pdf (979297)
 
Development and Validation of a Dissolution Test for Meloxicam and Pridinol Mesylate in their Combined Tablet Formulation. Silvana E. Vignaduzzo, Patricia M. Castellano y Teodoro S. Kaufman. Indian J. Pharm Sci. 72, 197-203 (2010). Indian J Pharm Sci 2010 72 197.pdf (2726490)
 
A Novel Chemometric Strategy for the Estimation of Extra Virgin Olive Oil Adulteration with Edible Oils. Rubén M. Maggio, Lorenzo Cerretani, Emma Chiavaro, Teodoro S. Kaufman y Alessandra Bendini. Food Control 21, 890-895 (2010). Food Control 2010 21 890.pdf (1726669)
 
Development and Validation of an HPLC Method for the Determination of Process-Related Impurities in Pridinol Mesylate, Employing Experimental Designs. Romina M. Bianchini, Patricia M. Castellano y Teodoro S. Kaufman. Anal. Chim. Acta 654, 141-147 (2009). Anal Chim Acta 2009 654 141.pdf (589432)
 
New Inhibitors of the Complement System Inspired in K76-COOH. A SAR Study of Filifolinol Derivatives Through Modifications of the C3’ Position. Enrique L. Larghi, María A. Operto, Rene Torres y Teodoro S. Kaufman. Bioorg. Med. Chem. Lett. 19, 6172-6175 (2009). Bioorg Med Chem Lett 2009 19 6172.pdf (454761)
 
Electrocyclization-Mediated Approach to 2-Methyltriclisine, an Unnatural Analog of the Azafluoranthene Alkaloid Triclisine. Claudio C. Silveira, Enrique L. Larghi, Samuel R. Mendes, Andrea B. J. Bracca, Francieli Rinaldi y Teodoro S. Kaufman. Eur. J. Org. Chem. 4637-4645 (2009). Eur J Org Chem 2009 4637.pdf (236467)
 
PCA-CR Analysis of Dissolution Profiles. A Chemometric Approach to Probe the Polymorphic Form of the Active Pharmaceutical Ingredient in a Drug Product. Rubén M. Maggio, Patricia M. Castellano y Teodoro S. Kaufman. Int. J. Pharm. 378, 187-193 (2009). Int J Pharm 2009 378 187.pdf (747085)
 
Aaptamine and Related Compounds. Their Isolation, Chemical Syntheses and Biological Activities. Enrique L. Larghi, María L. Bohn y Teodoro S. Kaufman. Tetrahedron 65, 4257-4282 (2009). Tetrahedron 2009 65 4257.pdf (1757382)
 
Monitoring of Fatty Acid Composition in Virgin Olive Oil by Fourier Transformed Infrared Spectroscopy coupled with Partial Least Squares. Rubén M. Maggio, Teodoro S. Kaufman, Michele Del Carlo, Lorenzo Cerretani, Alessandra Bendini, Angelo Cichelli y Dario Compagnone. Food Chem. 114, 1549-1554 (2009). Food Chem 2009 114 1549.pdf (371387)
 
Stress Studies on Pridinol Mesylate and Synthesis of Relevant Impurities. Development and Validation of an HPLC Method for Their Determination. Romina M. Bianchini, Patricia M. Castellano y Teodoro S. Kaufman. J. Pharm. Biomed. Anal.. 48, 1151-1160 (2008). J Pharm Biomed Anal 2008 48 1151.pdf (1393767)
 
A Multivariate Approach for the Simultaneous Determination of Losartan Potassium and Hydrochlorothiazide in a Combined Pharmaceutical Tablet Formulation. Rubén M. Maggio, Patricia M. Castellano y Teodoro S. Kaufman. Anal. Bioanal. Chem. 391, 2949-2955 (2008). Anal Bioanal Chem 2008 391 2949.pdf (153908)
 
A New Principal Component Analysis-Based Approach for testing ‘similarity’ of Drug Dissolution Profiles. Rubén M. Maggio, Patricia M. Castellano y Teodoro S. Kaufman. Eur. J. Pharm. Sci. 34, 66-77 (2008). Eur J Pharm Sci 2008 34 66.pdf (1131197)
 
Method Development and Validation for the Simultaneous Determination of Meloxicam and Pridinol Mesylate Using RP-HPLC and Application in Drug Formulations. Silvana E. Vignaduzzo, Patricia M. Castellano y Teodoro S. Kaufman. J. Pharm. Biomed. Anal. 46, 219-225 (2008). J Pharm Biomed Anal 2008 46 219.pdf (444157)
 
Evaluación y Análisis de Parámetros de Calidad de Comprimidos de Paracetamol. María A. Operto, Patricia M. Castellano y Teodoro S. Kaufman. Latin Am. J. Pharm. 27, 603-607 (2008). Latin Am J Pharm 2008 27 603.pdf (112399)
 
Formulation, Rubén M. Maggio, Patricia M. Castellano, Silvana E. Vignaduzzo y Teodoro S. Kaufman. J. Pharm. Biomed. Anal. 45, 804-810 (2007). J Pharm Biomed Anal 2007 45 804.pdf (212799)
 
PLS and first derivative of ratio spectra mehtods for determination of hydrochlorothiazide and propranolol hydrochloride in tablets. Silvana E. Vignaduzzo, Rubén M. Maggio, Patricia M. Castellano y Teodoro S. Kaufman. Anal. Bioanal. Chem. 386, 2239-2244 (2006). Anal Bioanal Chem 2006 386 2239.pdf (205944)
 
Application of a Chemometric Method for the Simultaneous Determination of Acetaminophen and diclofenac in content-uniformity and drug –dissolution studies. Silvana E. Vignaduzzo, Patricia M. Castellano, Rubén M. Maggio y Teodoro S. Kaufman. Anal. Bioanal. Chem. 382, 1711-1714 (2005). Anal Bioanal Chem 2005 382 1711.pdf (225063)
 
Chemometric Determination of Amiloride Hydrochloride, Atenolol, Hydrochlorothiazide and Timolol Maleate in Synthetic Mixtures and Pharmaceutical Formulations. Mónica C. F. Ferraro, Patricia M. Castellano y Teodoro S. Kaufman. J. Pharm. Biomed. Anal. 34, 305-314 (2004). J Pharm Biomed Anal 2004 34 305.pdf (104386)
 
Chemometrics-Assisted Simultaneous Determination of Atenolol and Chlorthalidone in Synthetic Binary Mixtures and Pharmaceutical Dosage Forms. Mónica C. F. Ferraro, Patricia M. Castellano y Teodoro S. Kaufman. Anal. Bioanal. Chem. 377, 1159-1164 (2003). Anal Bioanal Chem 2003 377 1159.pdf (213374)
 
Simultaneous Determination of Amiloride Hydrochloride and Hydrochlorothiazide in Synthetic Samples and Pharmaceutical Formulations by Multivariate Analysis of Spectrophotometric Data. Mónica C. F. Ferraro, Patricia M. Castellano y Teodoro S. Kaufman. J. Pharm. Biomed. Anal. 30, 1121-1131 (2002). J Pharm Biomed Anal 2002 30 1121.pdf (170669)
 
A Spectrophotometric-Partial Least Squares (PLS-1) Method for the Simultaneous Determination of Furosemide and Amiloride Hydrochloride in Pharmaceutical Formulations. Mónica C. F. Ferraro, Patricia M. Castellano y Teodoro S. Kaufman. J. Pharm. Biomed. Anal. 26, 443-451 (2001). J Pharm Biomed Anal 2001 26 443.pdf (118323)